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Product Name: IGF-1 LR3
CAS: 143045-27-6
Molecular Mass: 9117.60 g/mol
Molecular Formula: C400H625N111O115S9
Storage: Peptides should be stored in a dry, cool, dark place. For best preservation, store at 4°C or colder away from bright light.
Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1).
Insulin-like Growth Factor 1 (IGF-1) is a vital protein that plays an integral role in human growth and development. This recombinant human protein, which belongs to the insulin-like growth factor family, consists of 70 amino acids and functions similarly to insulin. It is involved in the regulation of various bodily processes, including cell growth, development, and differentiation, through endocrine, autocrine, and paracrine pathways.
One of the intriguing aspects of IGF-1 is its connection to aging. Research suggests that mutations in the IGF-1 gene can increase lifespan in laboratory animals, highlighting its potential impact on longevity. In children, IGF-1 is essential for stimulating cell growth and differentiation, while in adults, it continues to exert anabolic effects, promoting tissue growth and maintenance.
IGF-1 operates within a complex network of growth factors, receptors, and binding proteins that mediate cell proliferation, differentiation, and apoptosis. These growth factors are low-molecular-weight proteins present in nearly all tissues, where they regulate cell division, growth, and migration. In the skin, for instance, they are crucial for the migration and development of epithelial cells and stimulate cell division.
Often referred to as somatomedin C, IGF-1 serves as a key mediator of the growth hormone (HGH) effects. It is primarily produced by liver hepatocytes in response to growth hormone stimulation. The liver’s production of IGF-1 is influenced by various hormones, including sex steroids, thyroid hormones, glucocorticoids, and insulin. Insulin, androgens, and estrogens tend to enhance IGF-1 secretion, whereas glucocorticoids inhibit it. This interplay explains the synergy between these hormones in growth and development processes and the inhibitory impact of glucocorticoids on growth and puberty.
Throughout life, IGF-1 levels fluctuate, peaking during adolescence and dipping during childhood and old age. Despite these variations, IGF-1 remains a crucial anabolic hormone. It is secreted by various tissues, with the liver being the primary source, releasing IGF-1 into the bloodstream to act as an endocrine hormone. Other tissues, including cartilage cells, also secrete IGF-1, where it functions locally as a paracrine hormone.
In recent years, IGF-1 has garnered attention in the sports world as a doping agent, featuring in numerous high-profile doping cases. Its ability to enhance growth and performance makes it a substance of interest and concern in athletic communities.
IGF-1 LR3is often the secret weapon of professional bodybuilders. It is the use of this product that is the next step for progress after anabolic steroids and growth hormone, which have long gained popularity among the world of PEDs lovers.
The IGF-1 LR3 product is very broad-acting and can be used both for fat burning, acceleration of injury healing and strengthening of the articular-ligamentous apparatus, gaining muscle mass and accelerated recovery after exertion, because the substance also affects the recovery of the nervous system. IGF-1 LR3 software has a rich range of properties that are suitable for many purposes and will be an excellent addition to any of your courses, whether it is a set of muscle mass or pre-competitive training.
Beginners: 20-40 mcg per day
Intermediate: 40-60 mcg per day
Advanced: 60-100 mcg per day
Typically, 4-6 weeks, followed by a break of equal length to avoid desensitization.
Frequency: Daily injections
Timing: Administered in the morning or post-workout to maximize absorption and effectiveness.
Injection Site: Subcutaneous or intramuscular injections, rotating sites to prevent tissue damage.
Example
| Timeframe (weeks) | Daily IGF-1 LR3 dosage |
|---|---|
| 1-6 | 20-100 mcg (consider initiating at lower dose to assess tolerance) |
| 7-12 | Washout |
| 13-18 | 20-100 mcg |
| 19-24 | Washout |
After injection of IGF-1 LR3 (insulin-like growth factor 1, long variant), the concentration in the blood reaches a peak after about 1-2 hours. The effects can persist for 24-30 hours, as IGF-1 LR3 has a longer half-life compared to conventional IGF-1
Overdose can cause the side effects that are listed above. Most often, this is hypoglycemia – a decrease in sugar below the 3.5 mmol/l mark. In this case, it is necessary to eat a certain amount of carbohydrate food until the condition stabilizes.
Intramuscular or subcutaneous injections using insulin syringes.
If you stop taking the drug three days before testing, no one will be able to detect the substance in the blood.
